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Seamie live on the ocean floor, where many barb-like arms surround the center spout, which occasionally shoots out built-up ink. The nutrient-rich ink is eaten by many other aquatic Pokémon in the region.

People in ancient times imagined that Seamie were transformed from the reflections of stars that twinkled on gentle waves at night. The poisonous barbs all over its body are highly valued as ingredients for making traditional herbal medicine.