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Nidoroc is primarily active at night, traveling in packs across mountainous areas. The fur on its head is covered in a thick poison that can cause nausea, making it difficult for foes to approach.

It goads its enemies into attacking, withstands the hits, and in return, delivers a headbutt, crushing their bones with its rocky mane. Its highly toxic barbs are thought to have developed as protection for this small-bodied Pokémon.